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Cytokine biomarkers to predict antitumor responses to nivolumab suggested in a phase 2 study for advanced melanoma
Promising antitumor activities of nivolumab, a fully humanized IgG4 inhibitor antibody against the programmed death‐1 protein, were suggested in previous phase 1 studies. The present phase 2, single‐arm study (JAPIC‐CTI #111681) evaluated the antitumor activities of nivolumab and explored its predic...
Autores principales: | Yamazaki, Naoya, Kiyohara, Yoshio, Uhara, Hisashi, Iizuka, Hajime, Uehara, Jiro, Otsuka, Fujio, Fujisawa, Yasuhiro, Takenouchi, Tatsuya, Isei, Taiki, Iwatsuki, Keiji, Uchi, Hiroshi, Ihn, Hironobu, Minami, Hironobu, Tahara, Hideaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448619/ https://www.ncbi.nlm.nih.gov/pubmed/28266140 http://dx.doi.org/10.1111/cas.13226 |
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