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Anti‐cancer stem cell activity of a hedgehog inhibitor GANT61 in estrogen receptor‐positive breast cancer cells

Estradiol (E2) increases not only the cell growth but also the cancer stem cell (CSC) proportion in estrogen receptor (ER)‐positive breast cancer cells. It has been suggested that the non‐canonical hedgehog (Hh) pathway activated by E2 plays an important role in the regulation of CSC proportion in E...

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Detalles Bibliográficos
Autores principales: Kurebayashi, Junichi, Koike, Yoshikazu, Ohta, Yusuke, Saitoh, Wataru, Yamashita, Tetsumasa, Kanomata, Naoki, Moriya, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448645/
https://www.ncbi.nlm.nih.gov/pubmed/28211214
http://dx.doi.org/10.1111/cas.13205