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Targeting innate immunity to downmodulate adaptive immunity and reverse type 1 diabetes
Type 1 diabetes (T1D) is characterized by specific destruction of pancreatic insulin-producing beta cells accompanied by evidence of beta-cell-directed autoimmunity such as autoreactive T cells and islet autoantibodies (IAAs). Currently, T1D cannot be prevented or reversed in humans. T1D is easy to...
Autores principales: | Itoh, Arata, Ridgway, William M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448691/ https://www.ncbi.nlm.nih.gov/pubmed/28580341 http://dx.doi.org/10.2147/ITT.S117264 |
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