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Development of antiproliferative long-circulating liposomes co-encapsulating doxorubicin and curcumin, through the use of a quality-by-design approach
The aim of this work was to use the quality-by-design (QbD) approach in the development of long-circulating liposomes co-loaded with curcumin (CUR) and doxorubicin (DOX) and to evaluate the cytotoxic potential of these liposomes in vitro using C26 murine colon carcinoma cell line. Based on a risk as...
Autores principales: | Tefas, Lucia Ruxandra, Sylvester, Bianca, Tomuta, Ioan, Sesarman, Alina, Licarete, Emilia, Banciu, Manuela, Porfire, Alina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448697/ https://www.ncbi.nlm.nih.gov/pubmed/28579758 http://dx.doi.org/10.2147/DDDT.S129008 |
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