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Study of 2-aminoquinolin-4(1H)-one under Mannich and retro-Mannich reaction

2-Aminoquinolin-4(1H)-one was reacted with various primary/secondary amines and paraformaldehyde under Mannich reaction conditions. In the case of secondary amines, the reaction in N,N-dimethylformamide yielded expected Mannich products accompanied with 3,3'-methylenebis(2-aminoquinolin-4(1H)-o...

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Detalles Bibliográficos
Autores principales: Funk, Petr, Motyka, Kamil, Soural, Miroslav, Malon, Michal, Koshino, Hiroyuki, Kusz, Joachim, Hlavac, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448738/
https://www.ncbi.nlm.nih.gov/pubmed/28557987
http://dx.doi.org/10.1371/journal.pone.0175364