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The exceptionally high rate of spontaneous mutations in the polymerase delta proofreading exonuclease-deficient Saccharomyces cerevisiae strain starved for adenine
BACKGROUND: Mutagenesis induced in the yeast Saccharomyces cerevisiae by starvation for nutrilites is a well-documented phenomenon of an unknown mechanism. We have previously shown that the polymerase delta proofreading activity controls spontaneous mutagenesis in cells starved for histidine. To obt...
Autores principales: | Achilli, Alessandro, Matmati, Nabil, Casalone, Enrico, Morpurgo, Giorgio, Lucaccioni, Angela, Pavlov, Youri I, Babudri, Nora |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544876/ https://www.ncbi.nlm.nih.gov/pubmed/15617571 http://dx.doi.org/10.1186/1471-2156-5-34 |
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