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The Drosophila orthologue of the INT6 onco-protein regulates mitotic microtubule growth and kinetochore structure
INT6/eIF3e is a highly conserved component of the translation initiation complex that interacts with both the 26S proteasome and the COP9 signalosome, two complexes implicated in ubiquitin-mediated protein degradation. The INT6 gene was originally identified as the insertion site of the mouse mammar...
Autores principales: | Renda, Fioranna, Pellacani, Claudia, Strunov, Anton, Bucciarelli, Elisabetta, Naim, Valeria, Bosso, Giuseppe, Kiseleva, Elena, Bonaccorsi, Silvia, Sharp, David J., Khodjakov, Alexey, Gatti, Maurizio, Somma, Maria Patrizia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448806/ https://www.ncbi.nlm.nih.gov/pubmed/28505193 http://dx.doi.org/10.1371/journal.pgen.1006784 |
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