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Novel Textile Scaffolds Generated by Flock Technology for Tissue Engineering of Bone and Cartilage

Textile scaffolds can be found in a variety of application areas in regenerative medicine and tissue engineering. In the present study we used electrostatic flocking—a well-known textile technology—to produce scaffolds for tissue engineering of bone. Flock scaffolds stand out due to their unique str...

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Detalles Bibliográficos
Autores principales: Walther, Anja, Hoyer, Birgit, Springer, Armin, Mrozik, Birgit, Hanke, Thomas, Cherif, Chokri, Pompe, Wolfgang, Gelinsky, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448925/
https://www.ncbi.nlm.nih.gov/pubmed/28817062
http://dx.doi.org/10.3390/ma5030540
Descripción
Sumario:Textile scaffolds can be found in a variety of application areas in regenerative medicine and tissue engineering. In the present study we used electrostatic flocking—a well-known textile technology—to produce scaffolds for tissue engineering of bone. Flock scaffolds stand out due to their unique structure: parallel arranged fibers that are aligned perpendicularly to a substrate, resulting in mechanically stable structures with a high porosity. In compression tests we demonstrated good mechanical properties of such scaffolds and in cell culture experiments we showed that flock scaffolds allow attachment and proliferation of human mesenchymal stem cells and support their osteogenic differentiation. These matrices represent promising scaffolds for tissue engineering.