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Novel Textile Scaffolds Generated by Flock Technology for Tissue Engineering of Bone and Cartilage
Textile scaffolds can be found in a variety of application areas in regenerative medicine and tissue engineering. In the present study we used electrostatic flocking—a well-known textile technology—to produce scaffolds for tissue engineering of bone. Flock scaffolds stand out due to their unique str...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448925/ https://www.ncbi.nlm.nih.gov/pubmed/28817062 http://dx.doi.org/10.3390/ma5030540 |
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author | Walther, Anja Hoyer, Birgit Springer, Armin Mrozik, Birgit Hanke, Thomas Cherif, Chokri Pompe, Wolfgang Gelinsky, Michael |
author_facet | Walther, Anja Hoyer, Birgit Springer, Armin Mrozik, Birgit Hanke, Thomas Cherif, Chokri Pompe, Wolfgang Gelinsky, Michael |
author_sort | Walther, Anja |
collection | PubMed |
description | Textile scaffolds can be found in a variety of application areas in regenerative medicine and tissue engineering. In the present study we used electrostatic flocking—a well-known textile technology—to produce scaffolds for tissue engineering of bone. Flock scaffolds stand out due to their unique structure: parallel arranged fibers that are aligned perpendicularly to a substrate, resulting in mechanically stable structures with a high porosity. In compression tests we demonstrated good mechanical properties of such scaffolds and in cell culture experiments we showed that flock scaffolds allow attachment and proliferation of human mesenchymal stem cells and support their osteogenic differentiation. These matrices represent promising scaffolds for tissue engineering. |
format | Online Article Text |
id | pubmed-5448925 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-54489252017-07-28 Novel Textile Scaffolds Generated by Flock Technology for Tissue Engineering of Bone and Cartilage Walther, Anja Hoyer, Birgit Springer, Armin Mrozik, Birgit Hanke, Thomas Cherif, Chokri Pompe, Wolfgang Gelinsky, Michael Materials (Basel) Article Textile scaffolds can be found in a variety of application areas in regenerative medicine and tissue engineering. In the present study we used electrostatic flocking—a well-known textile technology—to produce scaffolds for tissue engineering of bone. Flock scaffolds stand out due to their unique structure: parallel arranged fibers that are aligned perpendicularly to a substrate, resulting in mechanically stable structures with a high porosity. In compression tests we demonstrated good mechanical properties of such scaffolds and in cell culture experiments we showed that flock scaffolds allow attachment and proliferation of human mesenchymal stem cells and support their osteogenic differentiation. These matrices represent promising scaffolds for tissue engineering. MDPI 2012-03-22 /pmc/articles/PMC5448925/ /pubmed/28817062 http://dx.doi.org/10.3390/ma5030540 Text en © 2012 by the authors. licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Article Walther, Anja Hoyer, Birgit Springer, Armin Mrozik, Birgit Hanke, Thomas Cherif, Chokri Pompe, Wolfgang Gelinsky, Michael Novel Textile Scaffolds Generated by Flock Technology for Tissue Engineering of Bone and Cartilage |
title | Novel Textile Scaffolds Generated by Flock Technology for Tissue Engineering of Bone and Cartilage |
title_full | Novel Textile Scaffolds Generated by Flock Technology for Tissue Engineering of Bone and Cartilage |
title_fullStr | Novel Textile Scaffolds Generated by Flock Technology for Tissue Engineering of Bone and Cartilage |
title_full_unstemmed | Novel Textile Scaffolds Generated by Flock Technology for Tissue Engineering of Bone and Cartilage |
title_short | Novel Textile Scaffolds Generated by Flock Technology for Tissue Engineering of Bone and Cartilage |
title_sort | novel textile scaffolds generated by flock technology for tissue engineering of bone and cartilage |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448925/ https://www.ncbi.nlm.nih.gov/pubmed/28817062 http://dx.doi.org/10.3390/ma5030540 |
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