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Novel Textile Scaffolds Generated by Flock Technology for Tissue Engineering of Bone and Cartilage

Textile scaffolds can be found in a variety of application areas in regenerative medicine and tissue engineering. In the present study we used electrostatic flocking—a well-known textile technology—to produce scaffolds for tissue engineering of bone. Flock scaffolds stand out due to their unique str...

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Detalles Bibliográficos
Autores principales: Walther, Anja, Hoyer, Birgit, Springer, Armin, Mrozik, Birgit, Hanke, Thomas, Cherif, Chokri, Pompe, Wolfgang, Gelinsky, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448925/
https://www.ncbi.nlm.nih.gov/pubmed/28817062
http://dx.doi.org/10.3390/ma5030540
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author Walther, Anja
Hoyer, Birgit
Springer, Armin
Mrozik, Birgit
Hanke, Thomas
Cherif, Chokri
Pompe, Wolfgang
Gelinsky, Michael
author_facet Walther, Anja
Hoyer, Birgit
Springer, Armin
Mrozik, Birgit
Hanke, Thomas
Cherif, Chokri
Pompe, Wolfgang
Gelinsky, Michael
author_sort Walther, Anja
collection PubMed
description Textile scaffolds can be found in a variety of application areas in regenerative medicine and tissue engineering. In the present study we used electrostatic flocking—a well-known textile technology—to produce scaffolds for tissue engineering of bone. Flock scaffolds stand out due to their unique structure: parallel arranged fibers that are aligned perpendicularly to a substrate, resulting in mechanically stable structures with a high porosity. In compression tests we demonstrated good mechanical properties of such scaffolds and in cell culture experiments we showed that flock scaffolds allow attachment and proliferation of human mesenchymal stem cells and support their osteogenic differentiation. These matrices represent promising scaffolds for tissue engineering.
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spelling pubmed-54489252017-07-28 Novel Textile Scaffolds Generated by Flock Technology for Tissue Engineering of Bone and Cartilage Walther, Anja Hoyer, Birgit Springer, Armin Mrozik, Birgit Hanke, Thomas Cherif, Chokri Pompe, Wolfgang Gelinsky, Michael Materials (Basel) Article Textile scaffolds can be found in a variety of application areas in regenerative medicine and tissue engineering. In the present study we used electrostatic flocking—a well-known textile technology—to produce scaffolds for tissue engineering of bone. Flock scaffolds stand out due to their unique structure: parallel arranged fibers that are aligned perpendicularly to a substrate, resulting in mechanically stable structures with a high porosity. In compression tests we demonstrated good mechanical properties of such scaffolds and in cell culture experiments we showed that flock scaffolds allow attachment and proliferation of human mesenchymal stem cells and support their osteogenic differentiation. These matrices represent promising scaffolds for tissue engineering. MDPI 2012-03-22 /pmc/articles/PMC5448925/ /pubmed/28817062 http://dx.doi.org/10.3390/ma5030540 Text en © 2012 by the authors. licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Walther, Anja
Hoyer, Birgit
Springer, Armin
Mrozik, Birgit
Hanke, Thomas
Cherif, Chokri
Pompe, Wolfgang
Gelinsky, Michael
Novel Textile Scaffolds Generated by Flock Technology for Tissue Engineering of Bone and Cartilage
title Novel Textile Scaffolds Generated by Flock Technology for Tissue Engineering of Bone and Cartilage
title_full Novel Textile Scaffolds Generated by Flock Technology for Tissue Engineering of Bone and Cartilage
title_fullStr Novel Textile Scaffolds Generated by Flock Technology for Tissue Engineering of Bone and Cartilage
title_full_unstemmed Novel Textile Scaffolds Generated by Flock Technology for Tissue Engineering of Bone and Cartilage
title_short Novel Textile Scaffolds Generated by Flock Technology for Tissue Engineering of Bone and Cartilage
title_sort novel textile scaffolds generated by flock technology for tissue engineering of bone and cartilage
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448925/
https://www.ncbi.nlm.nih.gov/pubmed/28817062
http://dx.doi.org/10.3390/ma5030540
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