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Cellular mRNA recruits the ribosome via eIF3-PABP bridge to initiate internal translation

IRES-mediated translation of key cell fate regulating genes has been implicated in tumorigenesis. Concerted action of canonical eukaryotic initiation factors and IRES transacting factors (ITAFs) was shown to regulate cellular IRES mediated translation; however, the precise molecular mechanism of rib...

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Detalles Bibliográficos
Autores principales:	Thakor, Nehal, Smith, M. Duane, Roberts, Luc, Faye, Mame Daro, Patel, Harshil, Wieden, Hans-Joachim, Cate, Jamie H. D., Holcik, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449081/ https://www.ncbi.nlm.nih.gov/pubmed/26828225 http://dx.doi.org/10.1080/15476286.2015.1137419

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