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The notorious R.N.A. in the spotlight - drug or target for the treatment of disease

mRNA is an attractive drug target for therapeutic interventions. In this review we highlight the current state, clinical trials, and developments in antisense therapy, including the classical approaches like RNaseH-dependent oligomers, splice-switching oligomers, aptamers, and therapeutic RNA interf...

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Detalles Bibliográficos
Autores principales:	Reautschnig, Philipp, Vogel, Paul, Stafforst, Thorsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449091/ https://www.ncbi.nlm.nih.gov/pubmed/27415589 http://dx.doi.org/10.1080/15476286.2016.1208323

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