GSK-3–mediated phosphorylation couples ER–Golgi transport and nuclear stabilization of the CREB-H transcription factor to mediate apolipoprotein secretion

CREB-H, an ER-anchored transcription factor, plays a key role in regulating secretion in metabolic pathways, particularly triglyceride homeostasis. It controls the production both of secretory pathway components and cargoes, including apolipoproteins ApoA-IV and ApoC-II, contributing to VLDL/HDL dis...

Descripción completa

Detalles Bibliográficos
Autores principales: Barbosa, Sónia, Carreira, Suzanne, O’Hare, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449154/
https://www.ncbi.nlm.nih.gov/pubmed/28381424
http://dx.doi.org/10.1091/mbc.E17-01-0075

Ejemplares similares

Ejemplares similares