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Insulin expressing hepatocytes not destroyed in transgenic NOD mice

BACKGROUND: The liver has been suggested as a suitable target organ for gene therapy of Type 1 diabetes. However, the fundamental issue whether insulin-secreting hepatocytes in vivo will be destroyed by the autoimmune processes that kill pancreatic β cells has not been fully addressed. It is possibl...

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Detalles Bibliográficos
Autores principales: Tabiin, Muhammad T, White, Christopher P, Morahan, Grant, Tuch, Bernard E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC544947/
https://www.ncbi.nlm.nih.gov/pubmed/15679918
http://dx.doi.org/10.1186/1740-2557-1-3