Cargando…

Global miRNA expression analysis identifies novel key regulators of plasma cell differentiation and malignant plasma cell

MicroRNAs (miRNAs) are small noncoding RNAs that attenuate expression of their mRNA targets. Here, we developed a new method and an R package, to easily infer candidate miRNA–mRNA target interactions that could be functional during a given biological process. Using this method, we described, for the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kassambara, Alboukadel, Jourdan, Michel, Bruyer, Angélique, Robert, Nicolas, Pantesco, Véronique, Elemento, Olivier, Klein, Bernard, Moreaux, Jérôme
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Computational Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449613/ https://www.ncbi.nlm.nih.gov/pubmed/28459970 http://dx.doi.org/10.1093/nar/gkx327

Ejemplares similares

Comprehensive characterization of the mutational landscape in multiple myeloma cell lines reveals potential drivers and pathways associated with tumor progression and drug resistance
por: Vikova, Veronika, et al.
Publicado: (2019)

Phenotypic Characterization of Diffuse Large B-Cell Lymphoma Cells and Prognostic Impact
por: Devin, Julie, et al.
Publicado: (2019)

RNA-sequencing data-driven dissection of human plasma cell differentiation reveals new potential transcription regulators
por: Kassambara, Alboukadel, et al.
Publicado: (2021)

Inhibition of DEPDC1A, a Bad Prognostic Marker in Multiple Myeloma, Delays Growth and Induces Mature Plasma Cell Markers in Malignant Plasma Cells
por: Kassambara, Alboukadel, et al.
Publicado: (2013)

RECQ helicases are deregulated in hematological malignancies in association with a prognostic value
por: Viziteu, Elena, et al.
Publicado: (2016)

RNA-Sequencing-Based Transcriptomic Score with Prognostic and Theranostic Values in Multiple Myeloma
por: Alaterre, Elina, et al.
Publicado: (2021)

GenomicScape: An Easy-to-Use Web Tool for Gene Expression Data Analysis. Application to Investigate the Molecular Events in the Differentiation of B Cells into Plasma Cells
por: Kassambara, Alboukadel, et al.
Publicado: (2015)

Characterization of human FCRL4-positive B cells
por: Jourdan, Michel, et al.
Publicado: (2017)

DNMTi/HDACi combined epigenetic targeted treatment induces reprogramming of myeloma cells in the direction of normal plasma cells
por: Bruyer, Angelique, et al.
Publicado: (2018)

Kinome expression profiling to target new therapeutic avenues in multiple myeloma
por: de Boussac, Hugues, et al.
Publicado: (2020)

Identification of Pluripotent and Adult Stem Cell Genes Unrelated to Cell Cycle and Associated with Poor Prognosis in Multiple Myeloma
por: Kassambara, Alboukadel, et al.
Publicado: (2012)

Drug metabolism and clearance system in tumor cells of patients with multiple myeloma
por: Hassen, Wafa, et al.
Publicado: (2014)

EZH2 is overexpressed in transitional preplasmablasts and is involved in human plasma cell differentiation
por: Herviou, Laurie, et al.
Publicado: (2019)

The Glycome of Normal and Malignant Plasma Cells
por: Moehler, Thomas M., et al.
Publicado: (2013)

Differential effects of lenalidomide during plasma cell differentiation
por: Jourdan, Michel, et al.
Publicado: (2016)

An epigenetic regulator-related score (EpiScore) predicts survival in patients with diffuse large B cell lymphoma and identifies patients who may benefit from epigenetic therapy
por: Szablewski, Vanessa, et al.
Publicado: (2018)

Role of Polycomb Complexes in Normal and Malignant Plasma Cells
por: Varlet, Emmanuel, et al.
Publicado: (2020)

A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy
por: Kassambara, Alboukadel, et al.
Publicado: (2014)

In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma
por: Maes, Ken, et al.
Publicado: (2014)

Residual malignant and normal plasma cells shortly after high dose melphalan and stem cell transplantation. Highlight of a putative therapeutic window in Multiple Myeloma?
por: Caraux, Anouk, et al.
Publicado: (2012)

Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells
por: Lub, Susanne, et al.
Publicado: (2015)

P843: METABOLOMIC CHARACTERIZATION OF HUMAN MULTIPLE MYELOMA CELL LINE TO STUDY TUMOR RESISTANCE TO DIFFERENT CLASSES OF THERAPEUTIC AGENTS
por: Steer, A., et al.
Publicado: (2022)

P844: CHARACTERIZATION OF MULTIPLE MYELOMA CELL LINES WITH ACQUIRED-RESISTANCE TO PROTEASOME INHIBITORS HIGHLIGHTS A LINK BETWEEN RESISTANCE AND METABOLIC DEREGULATION
por: De Boussac, H., et al.
Publicado: (2022)

EZH2 in normal hematopoiesis and hematological malignancies
por: Herviou, Laurie, et al.
Publicado: (2015)

PRC2 targeting is a therapeutic strategy for EZ score defined high-risk multiple myeloma patients and overcome resistance to IMiDs
por: Herviou, Laurie, et al.
Publicado: (2018)

Growth factors in multiple myeloma: a comprehensive analysis of their expression in tumor cells and bone marrow environment using Affymetrix microarrays
por: Mahtouk, Karène, et al.
Publicado: (2010)

Gene expression-based risk score in diffuse large B-cell lymphoma
por: Bret, Caroline, et al.
Publicado: (2012)

Nucleotide excision DNA repair pathway as a therapeutic target in patients with high-risk diffuse large B cell lymphoma
por: Bret, Caroline, et al.
Publicado: (2013)

Autophagy in Plasma Cell Ontogeny and Malignancy
por: Milan, Enrico, et al.
Publicado: (2016)

A gene expression signature shared by human mature oocytes and embryonic stem cells
por: Assou, Said, et al.
Publicado: (2009)

The hydroxymethylome of multiple myeloma identifies FAM72D as a 1q21 marker linked to proliferation
por: Chatonnet, Fabrice, et al.
Publicado: (2020)

Mast Cells and Angiogenesis in Human Plasma Cell Malignancies
por: Ribatti, Domenico, et al.
Publicado: (2019)

Induction of Malignant Plasma Cell Proliferation by Eosinophils
por: Wong, Tina W., et al.
Publicado: (2013)

A new method for class prediction based on signed-rank algorithms applied to Affymetrix(® )microarray experiments
por: Rème, Thierry, et al.
Publicado: (2008)

Comparison of Immune Response Assessment in Colon Cancer by Immunoscore (Automated Digital Pathology) and Pathologist Visual Scoring
por: Boquet, Isabelle, et al.
Publicado: (2022)

Editorial: Transcriptional control in normal and malignant B-lymphocytes
por: Moreaux, Jerome, et al.
Publicado: (2023)

Plasma miRNAs as biomarkers for endometriosis
por: Vanhie, A, et al.
Publicado: (2019)

Oleil Hydroxytyrosol (HTOL) Exerts Anti-Myeloma Activity by Antagonizing Key Survival Pathways in Malignant Plasma Cells
por: Todoerti, Katia, et al.
Publicado: (2021)

No Significant Difference between Plasma miRNAs and Plasma-Derived Exosomal miRNAs from Healthy People
por: Tian, Fei, et al.
Publicado: (2017)

Programming plasma cell survival
por: Klein, Ulf
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_61vrv49vgkviao2hv7tvhibod5