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A sensitivity analysis of RNA folding nearest neighbor parameters identifies a subset of free energy parameters with the greatest impact on RNA secondary structure prediction

Nearest neighbor parameters for estimating the folding energy changes of RNA secondary structures are used in structure prediction and analysis. Despite their widespread application, a comprehensive analysis of the impact of each parameter on the precision of calculations had not been conducted. To...

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Detalles Bibliográficos
Autores principales:	Zuber, Jeffrey, Sun, Hongying, Zhang, Xiaoju, McFadyen, Iain, Mathews, David H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449625/ https://www.ncbi.nlm.nih.gov/pubmed/28334976 http://dx.doi.org/10.1093/nar/gkx170

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