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MetaLIMS, a simple open-source laboratory information management system for small metagenomic labs

Background: As the cost of sequencing continues to fall, smaller groups increasingly initiate and manage larger sequencing projects and take on the complexity of data storage for high volumes of samples. This has created a need for low-cost laboratory information management systems (LIMS) that conta...

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Autores principales: Heinle, Cassie Elizabeth, Gaultier, Nicolas Paul Eugène, Miller, Dana, Purbojati, Rikky Wenang, Lauro, Federico M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449644/
https://www.ncbi.nlm.nih.gov/pubmed/28430964
http://dx.doi.org/10.1093/gigascience/gix025
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author Heinle, Cassie Elizabeth
Gaultier, Nicolas Paul Eugène
Miller, Dana
Purbojati, Rikky Wenang
Lauro, Federico M.
author_facet Heinle, Cassie Elizabeth
Gaultier, Nicolas Paul Eugène
Miller, Dana
Purbojati, Rikky Wenang
Lauro, Federico M.
author_sort Heinle, Cassie Elizabeth
collection PubMed
description Background: As the cost of sequencing continues to fall, smaller groups increasingly initiate and manage larger sequencing projects and take on the complexity of data storage for high volumes of samples. This has created a need for low-cost laboratory information management systems (LIMS) that contain flexible fields to accommodate the unique nature of individual labs. Many labs do not have a dedicated information technology position, so LIMS must also be easy to setup and maintain with minimal technical proficiency. Findings: MetaLIMS is a free and open-source web-based application available via GitHub. The focus of MetaLIMS is to store sample metadata prior to sequencing and analysis pipelines. Initially designed for environmental metagenomics labs, in addition to storing generic sample collection information and DNA/RNA processing information, the user can also add fields specific to the user's lab. MetaLIMS can also produce a basic sequencing submission form compatible with the proprietary Clarity LIMS system used by some sequencing facilities. To help ease the technical burden associated with web deployment, MetaLIMS options the use of commercial web hosting combined with MetaLIMS bash scripts for ease of setup. Conclusions: MetaLIMS overcomes key challenges common in LIMS by giving labs access to a low-cost and open-source tool that also has the flexibility to meet individual lab needs and an option for easy deployment. By making the web application open source and hosting it on GitHub, we hope to encourage the community to build upon MetaLIMS, making it more robust and tailored to the needs of more researchers.
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spelling pubmed-54496442017-07-31 MetaLIMS, a simple open-source laboratory information management system for small metagenomic labs Heinle, Cassie Elizabeth Gaultier, Nicolas Paul Eugène Miller, Dana Purbojati, Rikky Wenang Lauro, Federico M. Gigascience Technical Note Background: As the cost of sequencing continues to fall, smaller groups increasingly initiate and manage larger sequencing projects and take on the complexity of data storage for high volumes of samples. This has created a need for low-cost laboratory information management systems (LIMS) that contain flexible fields to accommodate the unique nature of individual labs. Many labs do not have a dedicated information technology position, so LIMS must also be easy to setup and maintain with minimal technical proficiency. Findings: MetaLIMS is a free and open-source web-based application available via GitHub. The focus of MetaLIMS is to store sample metadata prior to sequencing and analysis pipelines. Initially designed for environmental metagenomics labs, in addition to storing generic sample collection information and DNA/RNA processing information, the user can also add fields specific to the user's lab. MetaLIMS can also produce a basic sequencing submission form compatible with the proprietary Clarity LIMS system used by some sequencing facilities. To help ease the technical burden associated with web deployment, MetaLIMS options the use of commercial web hosting combined with MetaLIMS bash scripts for ease of setup. Conclusions: MetaLIMS overcomes key challenges common in LIMS by giving labs access to a low-cost and open-source tool that also has the flexibility to meet individual lab needs and an option for easy deployment. By making the web application open source and hosting it on GitHub, we hope to encourage the community to build upon MetaLIMS, making it more robust and tailored to the needs of more researchers. Oxford University Press 2017-04-18 /pmc/articles/PMC5449644/ /pubmed/28430964 http://dx.doi.org/10.1093/gigascience/gix025 Text en © The Authors 2017. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Technical Note
Heinle, Cassie Elizabeth
Gaultier, Nicolas Paul Eugène
Miller, Dana
Purbojati, Rikky Wenang
Lauro, Federico M.
MetaLIMS, a simple open-source laboratory information management system for small metagenomic labs
title MetaLIMS, a simple open-source laboratory information management system for small metagenomic labs
title_full MetaLIMS, a simple open-source laboratory information management system for small metagenomic labs
title_fullStr MetaLIMS, a simple open-source laboratory information management system for small metagenomic labs
title_full_unstemmed MetaLIMS, a simple open-source laboratory information management system for small metagenomic labs
title_short MetaLIMS, a simple open-source laboratory information management system for small metagenomic labs
title_sort metalims, a simple open-source laboratory information management system for small metagenomic labs
topic Technical Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449644/
https://www.ncbi.nlm.nih.gov/pubmed/28430964
http://dx.doi.org/10.1093/gigascience/gix025
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