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Prdx6 Upregulation by Curcumin Attenuates Ischemic Oxidative Damage via SP1 in Rats after Stroke

BACKGROUND: The role of Peroxiredoxin 6 (Prdx6) in brain ischemia remains unclear. Curcumin (Cur) treatment elicits neuroprotective effects against cerebral ischemic injury, and the associated mechanisms may involve Prdx6. In this study, we investigated whether Prdx6 and the transcription factor spe...

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Detalles Bibliográficos
Autores principales: Jia, Gongwei, Tan, Botao, Ma, Jingxi, Zhang, Lina, Jin, Xinhao, Li, Changqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449737/
https://www.ncbi.nlm.nih.gov/pubmed/28596967
http://dx.doi.org/10.1155/2017/6597401