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Prognostic significance of LINE-1 hypomethylation in oropharyngeal squamous cell carcinoma

BACKGROUND: Inclusion of new biomarkers to improve a personalized treatment approach for oropharyngeal squamous cell carcinoma (OPSCC) is urgently needed. Hypomethylation of the Long interspersed nucleotide element-1 (LINE-1) repetitive elements, a widely accepted surrogate of overall genomic DNA me...

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Detalles Bibliográficos
Autores principales:	Furlan, Carlo, Polesel, Jerry, Barzan, Luigi, Franchin, Giovanni, Sulfaro, Sandro, Romeo, Salvatore, Colizzi, Francesca, Rizzo, Aurora, Baggio, Vittorio, Giacomarra, Vittorio, Dei Tos, Angelo Paolo, Boscolo-Rizzo, Paolo, Vaccher, Emanuela, Dolcetti, Riccardo, Sigalotti, Luca, Fratta, Elisabetta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450111/ https://www.ncbi.nlm.nih.gov/pubmed/28572862 http://dx.doi.org/10.1186/s13148-017-0357-z

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