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Accurate characterization of the IFITM locus using MiSeq and PacBio sequencing shows genetic variation in Galliformes

BACKGROUND: Interferon inducible transmembrane (IFITM) proteins are effectors of the immune system widely characterized for their role in restricting infection by diverse enveloped and non-enveloped viruses. The chicken IFITM (chIFITM) genes are clustered on chromosome 5 and to date four genes have...

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Detalles Bibliográficos
Autores principales: Bassano, Irene, Ong, Swee Hoe, Lawless, Nathan, Whitehead, Thomas, Fife, Mark, Kellam, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450142/
https://www.ncbi.nlm.nih.gov/pubmed/28558694
http://dx.doi.org/10.1186/s12864-017-3801-8