Early anti-inflammatory intervention ameliorates axial disease in the proteoglycan-induced spondylitis mouse model of ankylosing spondylitis

BACKGROUND: Ankylosing spondylitis (AS) is characterised by immune-mediated arthritis and osteoproliferation, ultimately leading to joint ankylosis. Whether inflammation is necessary for osteoproliferation is controversial, fuelled by the unclear efficacy of anti-inflammatory treatments on radiograp...

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Detalles Bibliográficos
Autores principales: Tseng, Hsu-Wen, Glant, Tibor T., Brown, Matthew A., Kenna, Tony J., Thomas, Gethin P., Pettit, Allison R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450150/
https://www.ncbi.nlm.nih.gov/pubmed/28558827
http://dx.doi.org/10.1186/s12891-017-1600-7

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