Cargando…
A pharmacogenetic signature of high response to Copaxone in late-phase clinical-trial cohorts of multiple sclerosis
BACKGROUND: Copaxone is an efficacious and safe therapy that has demonstrated clinical benefit for over two decades in patients with relapsing forms of multiple sclerosis (MS). On an individual level, patients show variability in their response to Copaxone, with some achieving significantly higher r...
Autores principales: | Ross, Colin J., Towfic, Fadi, Shankar, Jyoti, Laifenfeld, Daphna, Thoma, Mathis, Davis, Matthew, Weiner, Brian, Kusko, Rebecca, Zeskind, Ben, Knappertz, Volker, Grossman, Iris, Hayden, Michael R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450152/ https://www.ncbi.nlm.nih.gov/pubmed/28569182 http://dx.doi.org/10.1186/s13073-017-0436-y |
Ejemplares similares
-
Physicochemical, biological, functional and toxicological characterization of the European follow-on glatiramer acetate product as compared with Copaxone
por: Melamed-Gal, S., et al.
Publicado: (2018) -
Letter to the Editor response: Nygaard et al.
por: Towfic, F., et al.
Publicado: (2017) -
Response to the Letter-to-the Editor by Cohen et al. concerning our eNeurologicalSci article, Melamed-Gal, et al. Physicochemical, biological, functional and toxicological characterization of the European follow-on glatiramer acetate product as compared with Copaxone. eNeurologicalSci 2018;12:19–30.https://doi.org/10.1016/j.ensci.2018.05.006
por: Melamed-Gal, Sigal, et al.
Publicado: (2018) -
Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse
por: Kusko, Rebecca, et al.
Publicado: (2018) -
Gene expression studies of a human monocyte cell line identify dissimilarities between differently manufactured glatiramoids
por: Kolitz, Sarah, et al.
Publicado: (2015)