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Multiscalar cellular automaton simulates in-vivo tumour-stroma patterns calibrated from in-vitro assay data
BACKGROUND: The tumour stroma -or tumour microenvironment- is an important constituent of solid cancers and it is thought to be one of the main obstacles to quantitative translation of drug activity between the preclinical and clinical phases of drug development. The tumour-stroma relationship has b...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450227/ https://www.ncbi.nlm.nih.gov/pubmed/28558757 http://dx.doi.org/10.1186/s12911-017-0461-1 |