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Identification and characterization of a cyclosporin binding cyclophilin from Staphylococcus aureus Newman
Cyclophilins, a class of peptidyl-prolyl cis-trans isomerase (PPIase) enzymes, are inhibited by cyclosporin A (CsA), an immunosuppressive drug. Staphylococcus aureus Newman, a pathogenic bacterium, carries a gene for encoding a putative cyclophilin (SaCyp). SaCyp shows significant homology with othe...
Autores principales: | Polley, Soumitra, Seal, Soham, Mahapa, Avisek, Jana, Biswanath, Biswas, Anindya, Mandal, Sukhendu, Sinha, Debabrata, Sau, Keya, Sau, Subrata |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450249/ https://www.ncbi.nlm.nih.gov/pubmed/28584448 http://dx.doi.org/10.6026/97320630013078 |
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