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Varicella associated pneumoniae in a pediatric population

BACKGROUND: Varicella pneumonia has been studied extensively in adults; it may also affect children and may require hospitalization. METHODS: We examined pneumonia complications in children hospitalized for varicella, over a 13 year period. RESULTS: Pneumonia occurred in 8.2% of children hospitalize...

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Autores principales: Bozzola, Elena, Gattinara, Guido Castelli, Bozzola, Mauro, Mirante, Nadia, Masci, Marco, Rossetti, Chiara, Krzystofiak, Andrzej, Nicolosi, Luciana, Cutrera, Renato, Lancella, Laura, Tozzi, Alberto Eugenio, Villani, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450302/
https://www.ncbi.nlm.nih.gov/pubmed/28558810
http://dx.doi.org/10.1186/s13052-017-0366-8
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author Bozzola, Elena
Gattinara, Guido Castelli
Bozzola, Mauro
Mirante, Nadia
Masci, Marco
Rossetti, Chiara
Krzystofiak, Andrzej
Nicolosi, Luciana
Cutrera, Renato
Lancella, Laura
Tozzi, Alberto Eugenio
Villani, Alberto
author_facet Bozzola, Elena
Gattinara, Guido Castelli
Bozzola, Mauro
Mirante, Nadia
Masci, Marco
Rossetti, Chiara
Krzystofiak, Andrzej
Nicolosi, Luciana
Cutrera, Renato
Lancella, Laura
Tozzi, Alberto Eugenio
Villani, Alberto
author_sort Bozzola, Elena
collection PubMed
description BACKGROUND: Varicella pneumonia has been studied extensively in adults; it may also affect children and may require hospitalization. METHODS: We examined pneumonia complications in children hospitalized for varicella, over a 13 year period. RESULTS: Pneumonia occurred in 8.2% of children hospitalized for varicella. The median length of hospitalization was 6 days. No statistically significant difference in length of stay was detected between immunodepressed children and previously healthy children. The hospitalization was on average shorter in patients who started antiviral therapy within 24 h of varicella onset. None of the included patients had been previously immunized for varicella. CONCLUSIONS: Our results support the need for increased awareness of current varicella prevention recommendations among both immunocompetent and immunodepressed individuals. In children affected by varicella, prompt antiviral therapy may be indicated to reduce the number of days of hospitalization.
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spelling pubmed-54503022017-06-01 Varicella associated pneumoniae in a pediatric population Bozzola, Elena Gattinara, Guido Castelli Bozzola, Mauro Mirante, Nadia Masci, Marco Rossetti, Chiara Krzystofiak, Andrzej Nicolosi, Luciana Cutrera, Renato Lancella, Laura Tozzi, Alberto Eugenio Villani, Alberto Ital J Pediatr Research BACKGROUND: Varicella pneumonia has been studied extensively in adults; it may also affect children and may require hospitalization. METHODS: We examined pneumonia complications in children hospitalized for varicella, over a 13 year period. RESULTS: Pneumonia occurred in 8.2% of children hospitalized for varicella. The median length of hospitalization was 6 days. No statistically significant difference in length of stay was detected between immunodepressed children and previously healthy children. The hospitalization was on average shorter in patients who started antiviral therapy within 24 h of varicella onset. None of the included patients had been previously immunized for varicella. CONCLUSIONS: Our results support the need for increased awareness of current varicella prevention recommendations among both immunocompetent and immunodepressed individuals. In children affected by varicella, prompt antiviral therapy may be indicated to reduce the number of days of hospitalization. BioMed Central 2017-05-30 /pmc/articles/PMC5450302/ /pubmed/28558810 http://dx.doi.org/10.1186/s13052-017-0366-8 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Bozzola, Elena
Gattinara, Guido Castelli
Bozzola, Mauro
Mirante, Nadia
Masci, Marco
Rossetti, Chiara
Krzystofiak, Andrzej
Nicolosi, Luciana
Cutrera, Renato
Lancella, Laura
Tozzi, Alberto Eugenio
Villani, Alberto
Varicella associated pneumoniae in a pediatric population
title Varicella associated pneumoniae in a pediatric population
title_full Varicella associated pneumoniae in a pediatric population
title_fullStr Varicella associated pneumoniae in a pediatric population
title_full_unstemmed Varicella associated pneumoniae in a pediatric population
title_short Varicella associated pneumoniae in a pediatric population
title_sort varicella associated pneumoniae in a pediatric population
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450302/
https://www.ncbi.nlm.nih.gov/pubmed/28558810
http://dx.doi.org/10.1186/s13052-017-0366-8
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