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mTORC1 signalling mediates PI3K-dependent large lipid droplet accumulation in Drosophila ovarian nurse cells

Insulin and insulin-like growth factor signalling (IIS), which is primarily mediated by the PI3-kinase (PI3K)/PTEN/Akt kinase signalling cassette, is a highly evolutionarily conserved pathway involved in co-ordinating growth, development, ageing and nutrient homeostasis with dietary intake. It contr...

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Detalles Bibliográficos
Autores principales: Mensah, Lawrence B., Goberdhan, Deborah C. I., Wilson, Clive
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450313/
https://www.ncbi.nlm.nih.gov/pubmed/28302666
http://dx.doi.org/10.1242/bio.022210