Ergosterol isolated from the basidiomycete Pleurotus salmoneostramineus affects Trypanosoma cruzi plasma membrane and mitochondria

BACKGROUND: Major drawbacks of the available treatment against Chagas disease (American trypanosomiasis) include its toxicity and therapeutic inefficiency in the chronic phase of the infection, which makes it a concern among neglected diseases. Therefore, the discovery of alternative drugs for treat...

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Detalles Bibliográficos
Autores principales: Alexandre, Tatiana Rodrigues, Lima, Marta Lopes, Galuppo, Mariana Kolos, Mesquita, Juliana Tonini, do Nascimento, Matilia Ana, dos Santos, Augusto Leonardo, Sartorelli, Patricia, Pimenta, Daniel Carvalho, Tempone, Andre Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450401/
https://www.ncbi.nlm.nih.gov/pubmed/28572816
http://dx.doi.org/10.1186/s40409-017-0120-0

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