Grid-based stochastic search for hierarchical gene-gene interactions in population-based genetic studies of common human diseases

BACKGROUND: Large-scale genetic studies of common human diseases have focused almost exclusively on the independent main effects of single-nucleotide polymorphisms (SNPs) on disease susceptibility. These studies have had some success, but much of the genetic architecture of common disease remains un...

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Detalles Bibliográficos
Autores principales: Moore, Jason H., Andrews, Peter C., Olson, Randal S., Carlson, Sarah E., Larock, Curt R., Bulhoes, Mario J., O’Connor, James P., Greytak, Ellen M., Armentrout, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450417/
https://www.ncbi.nlm.nih.gov/pubmed/28572842
http://dx.doi.org/10.1186/s13040-017-0139-3

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