The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea

The marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world. Today, cone snails have attracted attention for their remarkable venom components. Many conotoxins are proving valuable as res...

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Autores principales: Robinson, Samuel D., Li, Qing, Lu, Aiping, Bandyopadhyay, Pradip K., Yandell, Mark, Olivera, Baldomero M., Safavi-Hemami, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450551/
https://www.ncbi.nlm.nih.gov/pubmed/28531118
http://dx.doi.org/10.3390/md15050145
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author Robinson, Samuel D.
Li, Qing
Lu, Aiping
Bandyopadhyay, Pradip K.
Yandell, Mark
Olivera, Baldomero M.
Safavi-Hemami, Helena
author_facet Robinson, Samuel D.
Li, Qing
Lu, Aiping
Bandyopadhyay, Pradip K.
Yandell, Mark
Olivera, Baldomero M.
Safavi-Hemami, Helena
author_sort Robinson, Samuel D.
collection PubMed
description The marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world. Today, cone snails have attracted attention for their remarkable venom components. Many conotoxins are proving valuable as research tools, drug leads, and drugs. In this article, we present the venom gland transcriptome of C. gloriamaris, revealing this species’ conotoxin repertoire. More than 100 conotoxin sequences were identified, representing a valuable resource for future drug discovery efforts.
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spelling pubmed-54505512017-06-05 The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea Robinson, Samuel D. Li, Qing Lu, Aiping Bandyopadhyay, Pradip K. Yandell, Mark Olivera, Baldomero M. Safavi-Hemami, Helena Mar Drugs Article The marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world. Today, cone snails have attracted attention for their remarkable venom components. Many conotoxins are proving valuable as research tools, drug leads, and drugs. In this article, we present the venom gland transcriptome of C. gloriamaris, revealing this species’ conotoxin repertoire. More than 100 conotoxin sequences were identified, representing a valuable resource for future drug discovery efforts. MDPI 2017-05-20 /pmc/articles/PMC5450551/ /pubmed/28531118 http://dx.doi.org/10.3390/md15050145 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Robinson, Samuel D.
Li, Qing
Lu, Aiping
Bandyopadhyay, Pradip K.
Yandell, Mark
Olivera, Baldomero M.
Safavi-Hemami, Helena
The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea
title The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea
title_full The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea
title_fullStr The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea
title_full_unstemmed The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea
title_short The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea
title_sort venom repertoire of conus gloriamaris (chemnitz, 1777), the glory of the sea
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450551/
https://www.ncbi.nlm.nih.gov/pubmed/28531118
http://dx.doi.org/10.3390/md15050145
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