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Palmitoleate inhibits insulin transcription by activating the ERK1/2 pathway in rat pancreatic β-cells
The aim of the present study was to evaluate the effects of palmitoleate on insulin secretion and insulin mRNA levels, and to investigate the transcriptional regulation of insulin. INS-1 rat insulinoma cells were treated with palmitoleate in the presence of high glucose, and the amount of secreted i...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450653/ https://www.ncbi.nlm.nih.gov/pubmed/28587345 http://dx.doi.org/10.3892/etm.2017.4344 |