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Cytotoxic Indole Alkaloid 3α-Acetonyltabersonine Induces Glioblastoma Apoptosis via Inhibition of DNA Damage Repair

Cytotoxic indole alkaloids from Melodinus suaveolens, which belongs to the toxic plant family Apocynaceae, demonstrated impressive antitumor activities in many tumor types, but less application in glioblastoma, which is the lethal brain tumor. In the present study, we reported the anti-glioblastoma...

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Detalles Bibliográficos
Autores principales: Li, Yuan, Zhao, Yunli, Zhou, Xia, Ni, Wei, Dai, Zhi, Yang, Dong, Hao, Junjun, Luo, Lin, Liu, Yaping, Luo, Xiaodong, Zhao, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450698/
https://www.ncbi.nlm.nih.gov/pubmed/28452946
http://dx.doi.org/10.3390/toxins9050150

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