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Clinical relevance of gemstone spectral CT in the diagnosis of carotid atherosclerosis
A variety of imaging methods can be used in the diagnosis of atherosclerotic plaques. In the present study, we investigated the morphology and composition of atherosclerotic plaque associated with ischemic cerebral infarction by comparing gemstone spectral computed tomography (GSCT) and traditional...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450728/ https://www.ncbi.nlm.nih.gov/pubmed/28587323 http://dx.doi.org/10.3892/etm.2017.4342 |
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author | Wang, Jing-Jian Fan, Shu-Jie Wang, Long-Long Gao, Yan-Zhong Liu, Xiao-Juan |
author_facet | Wang, Jing-Jian Fan, Shu-Jie Wang, Long-Long Gao, Yan-Zhong Liu, Xiao-Juan |
author_sort | Wang, Jing-Jian |
collection | PubMed |
description | A variety of imaging methods can be used in the diagnosis of atherosclerotic plaques. In the present study, we investigated the morphology and composition of atherosclerotic plaque associated with ischemic cerebral infarction by comparing gemstone spectral computed tomography (GSCT) and traditional multi-slice CT (MSCT). In total, 200 patients were enrolled and divided into the experimental group (n=100), which underwent GSCT, and the control group (n=100), which underwent MSCT. All the cases were followed up to observe disease outcomes in patients with different atherosclerotic plaque types, and adverse events in carotid artery stenosis or cerebral infarction were recorded. Compared with traditional MSCT, sensitivity (93.2%), specificity (84.5%), and accuracy (91.0%) of GSCT were significantly higher. We found a correlation between vulnerable plaque of carotid atherosclerotic plaque and the occurrence of cerebral infarction. These results suggest the advantages of GSCT in analyzing atherosclerotic plaque and predicting the risk of ischemic cerebral infarction. |
format | Online Article Text |
id | pubmed-5450728 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-54507282017-06-05 Clinical relevance of gemstone spectral CT in the diagnosis of carotid atherosclerosis Wang, Jing-Jian Fan, Shu-Jie Wang, Long-Long Gao, Yan-Zhong Liu, Xiao-Juan Exp Ther Med Articles A variety of imaging methods can be used in the diagnosis of atherosclerotic plaques. In the present study, we investigated the morphology and composition of atherosclerotic plaque associated with ischemic cerebral infarction by comparing gemstone spectral computed tomography (GSCT) and traditional multi-slice CT (MSCT). In total, 200 patients were enrolled and divided into the experimental group (n=100), which underwent GSCT, and the control group (n=100), which underwent MSCT. All the cases were followed up to observe disease outcomes in patients with different atherosclerotic plaque types, and adverse events in carotid artery stenosis or cerebral infarction were recorded. Compared with traditional MSCT, sensitivity (93.2%), specificity (84.5%), and accuracy (91.0%) of GSCT were significantly higher. We found a correlation between vulnerable plaque of carotid atherosclerotic plaque and the occurrence of cerebral infarction. These results suggest the advantages of GSCT in analyzing atherosclerotic plaque and predicting the risk of ischemic cerebral infarction. D.A. Spandidos 2017-06 2017-04-13 /pmc/articles/PMC5450728/ /pubmed/28587323 http://dx.doi.org/10.3892/etm.2017.4342 Text en Copyright: © Wang et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Articles Wang, Jing-Jian Fan, Shu-Jie Wang, Long-Long Gao, Yan-Zhong Liu, Xiao-Juan Clinical relevance of gemstone spectral CT in the diagnosis of carotid atherosclerosis |
title | Clinical relevance of gemstone spectral CT in the diagnosis of carotid atherosclerosis |
title_full | Clinical relevance of gemstone spectral CT in the diagnosis of carotid atherosclerosis |
title_fullStr | Clinical relevance of gemstone spectral CT in the diagnosis of carotid atherosclerosis |
title_full_unstemmed | Clinical relevance of gemstone spectral CT in the diagnosis of carotid atherosclerosis |
title_short | Clinical relevance of gemstone spectral CT in the diagnosis of carotid atherosclerosis |
title_sort | clinical relevance of gemstone spectral ct in the diagnosis of carotid atherosclerosis |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450728/ https://www.ncbi.nlm.nih.gov/pubmed/28587323 http://dx.doi.org/10.3892/etm.2017.4342 |
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