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Clinical relevance of gemstone spectral CT in the diagnosis of carotid atherosclerosis

A variety of imaging methods can be used in the diagnosis of atherosclerotic plaques. In the present study, we investigated the morphology and composition of atherosclerotic plaque associated with ischemic cerebral infarction by comparing gemstone spectral computed tomography (GSCT) and traditional...

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Autores principales: Wang, Jing-Jian, Fan, Shu-Jie, Wang, Long-Long, Gao, Yan-Zhong, Liu, Xiao-Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450728/
https://www.ncbi.nlm.nih.gov/pubmed/28587323
http://dx.doi.org/10.3892/etm.2017.4342
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author Wang, Jing-Jian
Fan, Shu-Jie
Wang, Long-Long
Gao, Yan-Zhong
Liu, Xiao-Juan
author_facet Wang, Jing-Jian
Fan, Shu-Jie
Wang, Long-Long
Gao, Yan-Zhong
Liu, Xiao-Juan
author_sort Wang, Jing-Jian
collection PubMed
description A variety of imaging methods can be used in the diagnosis of atherosclerotic plaques. In the present study, we investigated the morphology and composition of atherosclerotic plaque associated with ischemic cerebral infarction by comparing gemstone spectral computed tomography (GSCT) and traditional multi-slice CT (MSCT). In total, 200 patients were enrolled and divided into the experimental group (n=100), which underwent GSCT, and the control group (n=100), which underwent MSCT. All the cases were followed up to observe disease outcomes in patients with different atherosclerotic plaque types, and adverse events in carotid artery stenosis or cerebral infarction were recorded. Compared with traditional MSCT, sensitivity (93.2%), specificity (84.5%), and accuracy (91.0%) of GSCT were significantly higher. We found a correlation between vulnerable plaque of carotid atherosclerotic plaque and the occurrence of cerebral infarction. These results suggest the advantages of GSCT in analyzing atherosclerotic plaque and predicting the risk of ischemic cerebral infarction.
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spelling pubmed-54507282017-06-05 Clinical relevance of gemstone spectral CT in the diagnosis of carotid atherosclerosis Wang, Jing-Jian Fan, Shu-Jie Wang, Long-Long Gao, Yan-Zhong Liu, Xiao-Juan Exp Ther Med Articles A variety of imaging methods can be used in the diagnosis of atherosclerotic plaques. In the present study, we investigated the morphology and composition of atherosclerotic plaque associated with ischemic cerebral infarction by comparing gemstone spectral computed tomography (GSCT) and traditional multi-slice CT (MSCT). In total, 200 patients were enrolled and divided into the experimental group (n=100), which underwent GSCT, and the control group (n=100), which underwent MSCT. All the cases were followed up to observe disease outcomes in patients with different atherosclerotic plaque types, and adverse events in carotid artery stenosis or cerebral infarction were recorded. Compared with traditional MSCT, sensitivity (93.2%), specificity (84.5%), and accuracy (91.0%) of GSCT were significantly higher. We found a correlation between vulnerable plaque of carotid atherosclerotic plaque and the occurrence of cerebral infarction. These results suggest the advantages of GSCT in analyzing atherosclerotic plaque and predicting the risk of ischemic cerebral infarction. D.A. Spandidos 2017-06 2017-04-13 /pmc/articles/PMC5450728/ /pubmed/28587323 http://dx.doi.org/10.3892/etm.2017.4342 Text en Copyright: © Wang et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Wang, Jing-Jian
Fan, Shu-Jie
Wang, Long-Long
Gao, Yan-Zhong
Liu, Xiao-Juan
Clinical relevance of gemstone spectral CT in the diagnosis of carotid atherosclerosis
title Clinical relevance of gemstone spectral CT in the diagnosis of carotid atherosclerosis
title_full Clinical relevance of gemstone spectral CT in the diagnosis of carotid atherosclerosis
title_fullStr Clinical relevance of gemstone spectral CT in the diagnosis of carotid atherosclerosis
title_full_unstemmed Clinical relevance of gemstone spectral CT in the diagnosis of carotid atherosclerosis
title_short Clinical relevance of gemstone spectral CT in the diagnosis of carotid atherosclerosis
title_sort clinical relevance of gemstone spectral ct in the diagnosis of carotid atherosclerosis
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450728/
https://www.ncbi.nlm.nih.gov/pubmed/28587323
http://dx.doi.org/10.3892/etm.2017.4342
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