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FGFR2 is required for airway basal cell self-renewal and terminal differentiation

Airway stem cells slowly self-renew and produce differentiated progeny to maintain homeostasis throughout the lifespan of an individual. Mutations in the molecular regulators of these processes may drive cancer or degenerative disease, but are also potential therapeutic targets. Conditionally deleti...

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Detalles Bibliográficos
Autores principales: Balasooriya, Gayan I., Goschorska, Maja, Piddini, Eugenia, Rawlins, Emma L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450841/
https://www.ncbi.nlm.nih.gov/pubmed/28348168
http://dx.doi.org/10.1242/dev.135681