Cargando…

CDC42 is required for epicardial and pro-epicardial development by mediating FGF receptor trafficking to the plasma membrane

The epicardium contributes to multiple cardiac lineages and is essential for cardiac development and regeneration. However, the mechanism of epicardium formation is unclear. This study aimed to establish the cellular and molecular mechanisms underlying the dissociation of pro-epicardial cells (PECs)...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jingjing, Miao, Lianjie, Zhao, Chen, Shaikh Qureshi, Wasay Mohiuddin, Shieh, David, Guo, Hua, Lu, Yangyang, Hu, Saiyang, Huang, Alice, Zhang, Lu, Cai, Chen-leng, Wan, Leo Q., Xin, Hongbo, Vincent, Peter, Singer, Harold A., Zheng, Yi, Cleaver, Ondine, Fan, Zhen-Chuan, Wu, Mingfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450847/
https://www.ncbi.nlm.nih.gov/pubmed/28465335
http://dx.doi.org/10.1242/dev.147173