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CDC42 is required for epicardial and pro-epicardial development by mediating FGF receptor trafficking to the plasma membrane
The epicardium contributes to multiple cardiac lineages and is essential for cardiac development and regeneration. However, the mechanism of epicardium formation is unclear. This study aimed to establish the cellular and molecular mechanisms underlying the dissociation of pro-epicardial cells (PECs)...
Autores principales: | Li, Jingjing, Miao, Lianjie, Zhao, Chen, Shaikh Qureshi, Wasay Mohiuddin, Shieh, David, Guo, Hua, Lu, Yangyang, Hu, Saiyang, Huang, Alice, Zhang, Lu, Cai, Chen-leng, Wan, Leo Q., Xin, Hongbo, Vincent, Peter, Singer, Harold A., Zheng, Yi, Cleaver, Ondine, Fan, Zhen-Chuan, Wu, Mingfu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450847/ https://www.ncbi.nlm.nih.gov/pubmed/28465335 http://dx.doi.org/10.1242/dev.147173 |
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