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Association of CYP17A1 Genetic Polymorphisms and Susceptibility to Essential Hypertension in the Southwest Han Chinese Population

BACKGROUND: The CYP17A1 gene encodes for cytochrome P450 enzyme CYP17A1, which is involved with the steroidogenic pathway including mineralocorticoids. The CYP17A1 polymorphisms might affect enzyme activity, then leading to a state of mineralocorticoid 11-deoxycorticosterone excess characterized by...

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Detalles Bibliográficos
Autores principales:	Li, Qian, Gao, Tangxin, Yuan, Yuncang, Wu, Yanrui, Huang, Qionglin, Xie, Fei, Ran, Pengzhan, Sun, Lijuan, Xiao, Chunjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2017
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450854/ https://www.ncbi.nlm.nih.gov/pubmed/28537227 http://dx.doi.org/10.12659/MSM.902109

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