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High-Resolution Computed Tomography and Pulmonary Function Findings of Occupational Arsenic Exposure in Workers
BACKGROUND: The number of studies where non-malignant pulmonary diseases are evaluated after occupational arsenic exposure is very few. AIMS: To investigate the effects of occupational arsenic exposure on the lung by high-resolution computed tomography and pulmonary function tests. STUDY DESIGN: Ret...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Galenos Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450867/ https://www.ncbi.nlm.nih.gov/pubmed/28443582 http://dx.doi.org/10.4274/balkanmedj.2016.0795 |
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author | Ergün, Recai Evcik, Ender Ergün, Dilek Ergan, Begüm Özkan, Esin Gündüz, Özge |
author_facet | Ergün, Recai Evcik, Ender Ergün, Dilek Ergan, Begüm Özkan, Esin Gündüz, Özge |
author_sort | Ergün, Recai |
collection | PubMed |
description | BACKGROUND: The number of studies where non-malignant pulmonary diseases are evaluated after occupational arsenic exposure is very few. AIMS: To investigate the effects of occupational arsenic exposure on the lung by high-resolution computed tomography and pulmonary function tests. STUDY DESIGN: Retrospective cross-sectional study. METHODS: In this study, 256 workers with suspected respiratory occupational arsenic exposure were included, with an average age of 32.9±7.8 years and an average of 3.5±2.7 working years. Hair and urinary arsenic levels were analysed. High-resolution computed tomography and pulmonary function tests were done. RESULTS: In workers with occupational arsenic exposure, high-resolution computed tomography showed 18.8% pulmonary involvement. In pulmonary involvement, pulmonary nodule was the most frequently seen lesion (64.5%). The other findings of pulmonary involvement were 18.8% diffuse interstitial lung disease, 12.5% bronchiectasis, and 27.1% bullae-emphysema. The mean age of patients with pulmonary involvement was higher and as they smoked more. The pulmonary involvement was 5.2 times higher in patients with skin lesions because of arsenic. Diffusing capacity of lung for carbon monoxide was significantly lower in patients with pulmonary involvement. CONCLUSION: Besides lung cancer, chronic occupational inhalation of arsenic exposure may cause non-malignant pulmonary findings such as bronchiectasis, pulmonary nodules and diffuse interstitial lung disease. So, in order to detect pulmonary involvement in the early stages, workers who experience occupational arsenic exposure should be followed by diffusion test and high-resolution computed tomography. |
format | Online Article Text |
id | pubmed-5450867 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Galenos Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-54508672017-06-01 High-Resolution Computed Tomography and Pulmonary Function Findings of Occupational Arsenic Exposure in Workers Ergün, Recai Evcik, Ender Ergün, Dilek Ergan, Begüm Özkan, Esin Gündüz, Özge Balkan Med J Original Article BACKGROUND: The number of studies where non-malignant pulmonary diseases are evaluated after occupational arsenic exposure is very few. AIMS: To investigate the effects of occupational arsenic exposure on the lung by high-resolution computed tomography and pulmonary function tests. STUDY DESIGN: Retrospective cross-sectional study. METHODS: In this study, 256 workers with suspected respiratory occupational arsenic exposure were included, with an average age of 32.9±7.8 years and an average of 3.5±2.7 working years. Hair and urinary arsenic levels were analysed. High-resolution computed tomography and pulmonary function tests were done. RESULTS: In workers with occupational arsenic exposure, high-resolution computed tomography showed 18.8% pulmonary involvement. In pulmonary involvement, pulmonary nodule was the most frequently seen lesion (64.5%). The other findings of pulmonary involvement were 18.8% diffuse interstitial lung disease, 12.5% bronchiectasis, and 27.1% bullae-emphysema. The mean age of patients with pulmonary involvement was higher and as they smoked more. The pulmonary involvement was 5.2 times higher in patients with skin lesions because of arsenic. Diffusing capacity of lung for carbon monoxide was significantly lower in patients with pulmonary involvement. CONCLUSION: Besides lung cancer, chronic occupational inhalation of arsenic exposure may cause non-malignant pulmonary findings such as bronchiectasis, pulmonary nodules and diffuse interstitial lung disease. So, in order to detect pulmonary involvement in the early stages, workers who experience occupational arsenic exposure should be followed by diffusion test and high-resolution computed tomography. Galenos Publishing 2017-05 2017-05-15 /pmc/articles/PMC5450867/ /pubmed/28443582 http://dx.doi.org/10.4274/balkanmedj.2016.0795 Text en © Copyright 2017, Trakya University Faculty of Medicine http://creativecommons.org/licenses/by/2.5/ Balkan Medical Journal |
spellingShingle | Original Article Ergün, Recai Evcik, Ender Ergün, Dilek Ergan, Begüm Özkan, Esin Gündüz, Özge High-Resolution Computed Tomography and Pulmonary Function Findings of Occupational Arsenic Exposure in Workers |
title | High-Resolution Computed Tomography and Pulmonary Function Findings of Occupational Arsenic Exposure in Workers |
title_full | High-Resolution Computed Tomography and Pulmonary Function Findings of Occupational Arsenic Exposure in Workers |
title_fullStr | High-Resolution Computed Tomography and Pulmonary Function Findings of Occupational Arsenic Exposure in Workers |
title_full_unstemmed | High-Resolution Computed Tomography and Pulmonary Function Findings of Occupational Arsenic Exposure in Workers |
title_short | High-Resolution Computed Tomography and Pulmonary Function Findings of Occupational Arsenic Exposure in Workers |
title_sort | high-resolution computed tomography and pulmonary function findings of occupational arsenic exposure in workers |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450867/ https://www.ncbi.nlm.nih.gov/pubmed/28443582 http://dx.doi.org/10.4274/balkanmedj.2016.0795 |
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