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Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants

The recent Middle East respiratory syndrome coronavirus (MERS-CoV), Ebola and Zika virus outbreaks exemplify the continued threat of (re-)emerging viruses to human health, and our inability to rapidly develop effective therapeutic countermeasures. Many viruses, including MERS-CoV and the Crimean-Con...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Bailey-Elkin, Ben A., Knaap, Robert C. M., Khare, Baldeep, Dalebout, Tim J., Johnson, Garrett G., van Kasteren, Puck B., McLeish, Nigel J., Gu, Jun, He, Wenguang, Kikkert, Marjolein, Mark, Brian L., Sidhu, Sachdev S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451084/
https://www.ncbi.nlm.nih.gov/pubmed/28542609
http://dx.doi.org/10.1371/journal.ppat.1006372