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Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants
The recent Middle East respiratory syndrome coronavirus (MERS-CoV), Ebola and Zika virus outbreaks exemplify the continued threat of (re-)emerging viruses to human health, and our inability to rapidly develop effective therapeutic countermeasures. Many viruses, including MERS-CoV and the Crimean-Con...
Autores principales: | Zhang, Wei, Bailey-Elkin, Ben A., Knaap, Robert C. M., Khare, Baldeep, Dalebout, Tim J., Johnson, Garrett G., van Kasteren, Puck B., McLeish, Nigel J., Gu, Jun, He, Wenguang, Kikkert, Marjolein, Mark, Brian L., Sidhu, Sachdev S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451084/ https://www.ncbi.nlm.nih.gov/pubmed/28542609 http://dx.doi.org/10.1371/journal.ppat.1006372 |
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