The influence of N-terminal acetylation on micelle-induced conformational changes and aggregation of α-Synuclein

The biological function of α-Synuclein has been related to binding to lipids and membranes but these interactions can also mediate α-Synuclein aggregation, which is associated to Parkinson’s disease and other neuropathologies. In brain tissue α-Synuclein is constitutively N-acetylated, a modificatio...

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Detalles Bibliográficos
Autores principales: Ruzafa, David, Hernandez-Gomez, Yuriko S., Bisello, Giovanni, Broersen, Kerensa, Morel, Bertrand, Conejero-Lara, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451137/
https://www.ncbi.nlm.nih.gov/pubmed/28562630
http://dx.doi.org/10.1371/journal.pone.0178576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451137/
https://www.ncbi.nlm.nih.gov/pubmed/28562630
http://dx.doi.org/10.1371/journal.pone.0178576

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