RISC-interacting clearing 3’- 5’ exoribonucleases (RICEs) degrade uridylated cleavage fragments to maintain functional RISC in Arabidopsis thaliana

RNA-induced silencing complex (RISC) is composed of miRNAs and AGO proteins. AGOs use miRNAs as guides to slice target mRNAs to produce truncated 5' and 3' RNA fragments. The 5' cleaved RNA fragments are marked with uridylation for degradation. Here, we identified novel cofactors of A...

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Detalles Bibliográficos
Autores principales: Zhang, Zhonghui, Hu, Fuqu, Sung, Min Woo, Shu, Chang, Castillo-González, Claudia, Koiwa, Hisashi, Tang, Guiliang, Dickman, Martin, Li, Pingwei, Zhang, Xiuren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451212/
https://www.ncbi.nlm.nih.gov/pubmed/28463111
http://dx.doi.org/10.7554/eLife.24466

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