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Monitoring multiple myeloma by next-generation sequencing of V(D)J rearrangements from circulating myeloma cells and cell-free myeloma DNA
Recent studies suggest that circulating tumor cells and cell-free DNA may represent powerful non-invasive tools for monitoring disease in patients with solid and hematologic malignancies. Here, we conducted a pilot study in 27 myeloma patients to explore the clonotypic V(D)J rearrangement for monito...
Autores principales: | Oberle, Anna, Brandt, Anna, Voigtlaender, Minna, Thiele, Benjamin, Radloff, Janina, Schulenkorf, Anita, Alawi, Malik, Akyüz, Nuray, März, Manuela, Ford, Christopher T., Krohn-Grimberghe, Artus, Binder, Mascha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451343/ https://www.ncbi.nlm.nih.gov/pubmed/28183851 http://dx.doi.org/10.3324/haematol.2016.161414 |
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