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Metabolomic profiling in a Hedgehog Interacting Protein (Hhip) murine model of chronic obstructive pulmonary disease

Genetic variants annotated to the hedgehog interacting protein (HHIP) are robustly associated with chronic obstructive pulmonary disease (COPD). Hhip haploinsufficiency in mice leads to increased susceptibility towards the development of emphysema following exposure to chronic cigarette smoke (CS)....

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Detalles Bibliográficos
Autores principales:	Wan, Emily S., Li, Yan, Lao, Taotao, Qiu, Weiliang, Jiang, Zhiqiang, Mancini, John D., Owen, Caroline A., Clish, Clary, DeMeo, Dawn L., Silverman, Edwin K., Zhou, Xiaobo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451406/ https://www.ncbi.nlm.nih.gov/pubmed/28566717 http://dx.doi.org/10.1038/s41598-017-02701-4

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