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Bone marrow niche-mimetics modulate HSPC function via integrin signaling

The bone marrow (BM) microenvironment provides critical physical cues for hematopoietic stem and progenitor cell (HSPC) maintenance and fate decision mediated by cell-matrix interactions. However, the mechanisms underlying matrix communication and signal transduction are less well understood. Contra...

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Detalles Bibliográficos
Autores principales: Kräter, Martin, Jacobi, Angela, Otto, Oliver, Tietze, Stefanie, Müller, Katrin, Poitz, David M., Palm, Sandra, Zinna, Valentina M., Biehain, Ulrike, Wobus, Manja, Chavakis, Triantafyllos, Werner, Carsten, Guck, Jochen, Bornhauser, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451425/
https://www.ncbi.nlm.nih.gov/pubmed/28566689
http://dx.doi.org/10.1038/s41598-017-02352-5