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FastGT: an alignment-free method for calling common SNVs directly from raw sequencing reads
We have developed a computational method that counts the frequencies of unique k-mers in FASTQ-formatted genome data and uses this information to infer the genotypes of known variants. FastGT can detect the variants in a 30x genome in less than 1 hour using ordinary low-cost server hardware. The ove...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451431/ https://www.ncbi.nlm.nih.gov/pubmed/28566690 http://dx.doi.org/10.1038/s41598-017-02487-5 |