Substrate Rigidity Controls Activation and Durotaxis in Pancreatic Stellate Cells

Pancreatic Ductal Adenocarcinoma (PDAC) is an aggressive malignancy characterised by the presence of extensive desmoplasia, thought to be responsible for the poor response of patients to systemic therapies. Pancreatic stellate cells (PSCs) are key mediators in the production of this fibrotic stroma,...

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Detalles Bibliográficos
Autores principales: Lachowski, Dariusz, Cortes, Ernesto, Pink, Daniel, Chronopoulos, Antonios, Karim, Saadia A., P. Morton, Jennifer, del Río Hernández, Armando E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451433/
https://www.ncbi.nlm.nih.gov/pubmed/28566691
http://dx.doi.org/10.1038/s41598-017-02689-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451433/
https://www.ncbi.nlm.nih.gov/pubmed/28566691
http://dx.doi.org/10.1038/s41598-017-02689-x

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