A novel CXCR4-targeted near-infrared (NIR) fluorescent probe (Peptide R-NIR750) specifically detects CXCR4 expressing tumors

C-X-C chemokine receptor 4 (CXCR4) is over-expressed in multiple human cancers and correlates with tumor aggressiveness, poor prognosis and increased risk for distant metastases. Imaging agents for CXCR4 are thus highly desirable. We developed a novel CXCR4-targeted near-infrared (NIR) fluorescent p...

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Detalles Bibliográficos
Autores principales: Santagata, Sara, Portella, Luigi, Napolitano, Maria, Greco, Adelaide, D’Alterio, Crescenzo, Barone, Maria Vittoria, Luciano, Antonio, Gramanzini, Matteo, Auletta, Luigi, Arra, Claudio, Zannetti, Antonella, Scala, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451476/
https://www.ncbi.nlm.nih.gov/pubmed/28566721
http://dx.doi.org/10.1038/s41598-017-02818-6

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