The Association between Age-Related Macular Degeneration and the Risk of Mortality

Studies have investigated the association between age-related macular degeneration (AMD) and subsequent risks of mortality, but results have been equivocal. We conducted a comprehensive analysis of prospective cohort studies to assess the association of AMD and the risk of mortality in the general p...

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Detalles Bibliográficos
Autores principales: Wang, Peipei, Wang, Jie, Ma, Jun, Jin, Ge, Guan, Xueqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451765/
https://www.ncbi.nlm.nih.gov/pubmed/28607930
http://dx.doi.org/10.1155/2017/3489603
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author Wang, Peipei
Wang, Jie
Ma, Jun
Jin, Ge
Guan, Xueqiang
author_facet Wang, Peipei
Wang, Jie
Ma, Jun
Jin, Ge
Guan, Xueqiang
author_sort Wang, Peipei
collection PubMed
description Studies have investigated the association between age-related macular degeneration (AMD) and subsequent risks of mortality, but results have been equivocal. We conducted a comprehensive analysis of prospective cohort studies to assess the association of AMD and the risk of mortality in the general population. We searched PubMed and EMBASE for trials published from 1980 to 2016. We included 11 cohort studies that reported relative risks with 95% confidence intervals for the association of AMD and mortality, involving 57,069 participants. In a random-effects model, the adjusted RR (95% confidence interval) associated with AMD was 1.09 (1.02–1.17) for all-cause mortality. Findings from this research provide support that persons with AMD had a higher subsequent risk of mortality than persons without AMD.
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spelling pubmed-54517652017-06-12 The Association between Age-Related Macular Degeneration and the Risk of Mortality Wang, Peipei Wang, Jie Ma, Jun Jin, Ge Guan, Xueqiang Biomed Res Int Research Article Studies have investigated the association between age-related macular degeneration (AMD) and subsequent risks of mortality, but results have been equivocal. We conducted a comprehensive analysis of prospective cohort studies to assess the association of AMD and the risk of mortality in the general population. We searched PubMed and EMBASE for trials published from 1980 to 2016. We included 11 cohort studies that reported relative risks with 95% confidence intervals for the association of AMD and mortality, involving 57,069 participants. In a random-effects model, the adjusted RR (95% confidence interval) associated with AMD was 1.09 (1.02–1.17) for all-cause mortality. Findings from this research provide support that persons with AMD had a higher subsequent risk of mortality than persons without AMD. Hindawi 2017 2017-05-18 /pmc/articles/PMC5451765/ /pubmed/28607930 http://dx.doi.org/10.1155/2017/3489603 Text en Copyright © 2017 Peipei Wang et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wang, Peipei
Wang, Jie
Ma, Jun
Jin, Ge
Guan, Xueqiang
The Association between Age-Related Macular Degeneration and the Risk of Mortality
title The Association between Age-Related Macular Degeneration and the Risk of Mortality
title_full The Association between Age-Related Macular Degeneration and the Risk of Mortality
title_fullStr The Association between Age-Related Macular Degeneration and the Risk of Mortality
title_full_unstemmed The Association between Age-Related Macular Degeneration and the Risk of Mortality
title_short The Association between Age-Related Macular Degeneration and the Risk of Mortality
title_sort association between age-related macular degeneration and the risk of mortality
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451765/
https://www.ncbi.nlm.nih.gov/pubmed/28607930
http://dx.doi.org/10.1155/2017/3489603
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