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The Transcription Factor Nrf2 Protects Angiogenic Capacity of Endothelial Colony-Forming Cells in High-Oxygen Radical Stress Conditions

BACKGROUND: Endothelial colony forming cells (ECFCs) have shown a promise in tissue engineering of vascular constructs, where they act as endothelial progenitor cells. After implantation, ECFCs are likely to be subjected to elevated reactive oxygen species (ROS). The transcription factor Nrf2 regula...

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Detalles Bibliográficos
Autores principales: Gremmels, Hendrik, de Jong, Olivier G., Hazenbrink, Diënty H., Fledderus, Joost O., Verhaar, Marianne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451769/
https://www.ncbi.nlm.nih.gov/pubmed/28607561
http://dx.doi.org/10.1155/2017/4680612