Cargando…
Sen1 has unique structural features grafted on the architecture of the Upf1‐like helicase family
The superfamily 1B (SF1B) helicase Sen1 is an essential protein that plays a key role in the termination of non‐coding transcription in yeast. Here, we identified the ~90 kDa helicase core of Saccharomyces cerevisiae Sen1 as sufficient for transcription termination in vitro and determined the corres...
Autores principales: | Leonaitė, Bronislava, Han, Zhong, Basquin, Jérôme, Bonneau, Fabien, Libri, Domenico, Porrua, Odil, Conti, Elena |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452015/ https://www.ncbi.nlm.nih.gov/pubmed/28408439 http://dx.doi.org/10.15252/embj.201696174 |
Ejemplares similares
-
Biochemical characterization of the helicase Sen1 provides new insights into the mechanisms of non-coding transcription termination
por: Han, Zhong, et al.
Publicado: (2017) -
Single-molecule characterization of extrinsic transcription termination by Sen1 helicase
por: Wang, S., et al.
Publicado: (2019) -
Termination of non‐coding transcription in yeast relies on both an RNA Pol II CTD interaction domain and a CTD‐mimicking region in Sen1
por: Han, Zhong, et al.
Publicado: (2020) -
Phospho-dependent and phospho-independent interactions of the helicase UPF1 with the NMD factors SMG5–SMG7 and SMG6
por: Chakrabarti, Sutapa, et al.
Publicado: (2014) -
Cryptic Transcription and Early Termination in the Control of Gene Expression
por: Colin, Jessie, et al.
Publicado: (2011)