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Administration of RANKL boosts thymic regeneration upon bone marrow transplantation

Cytoablative treatments lead to severe damages on thymic epithelial cells (TECs), which result in delayed de novo thymopoiesis and a prolonged period of T‐cell immunodeficiency. Understanding the mechanisms that govern thymic regeneration is of paramount interest for the recovery of a functional imm...

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Detalles Bibliográficos
Autores principales: Lopes, Noella, Vachon, Hortense, Marie, Julien, Irla, Magali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5452038/
https://www.ncbi.nlm.nih.gov/pubmed/28455312
http://dx.doi.org/10.15252/emmm.201607176